Influence of CXCR4/SDF-1 axis on E-cadherin/β-catenin complex expression in HT29 colon cancer cells

Figure 5 Effect of stromal cell-derived factor-1 on the phosphorylation of PI3K/AKT and β-catenin. A: Phosphorylation of PI3K/AKT and β-catenin after incubated with stromal cell-derived factor (SDF) at different periods of time (1, 5, 10, 15, 30, 60, 120 min and on days 1 and 2); B: Phosphorylation of PI3K/AKT and β-catenin after incubated with SDF-1 at different concentrations (5, 10, 20, 40 and 100 ng/mL) for 30 min; C and D: SDF-1 increases phosphorylation of PI3K/AKT and β-catenin in HT29 cells in a time- and dose-dependent manner. Bars represent mean ± SD of triplicate experiments. ^aP < 0.05.