Role of genetics in the diagnosis and prognosis of Crohn's disease

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Dec 28, 2011 (publication date) through Jul 23, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Dec 28, 2011; 17(48): 5246-5259
Published online Dec 28, 2011. doi: 10.3748/wjg.v17.i48.5246

Table 2 Predicted future developments in the genetics of Crohn’s disease

What lies ahead in the genetics of crohn’s disease
Gene-to-gene crosstalk and epistasis
Genome-wide association studies
Microarrays
Fine single nucleotide polymorphism analysis
Genetic consortium studies and genome-wide scans
Genome-wide association studies
Genetic consortium studies
Future perspectives
Functional studies to understand the mechanisms
Combining genetic data with functional data
Combination of a panel of clinical, biochemical, serological and genetic factors
Functional consequences of polymorphisms
Molecular and cellular mechanisms leading to Crohn’s disease
Predict disease outcomes
Redesigning the methods of treatment

Citation: Tsianos EV, Katsanos KH, Tsianos VE. Role of genetics in the diagnosis and prognosis of Crohn's disease. World J Gastroenterol 2011; 17(48): 5246-5259
URL: https://www.wjgnet.com/1007-9327/full/v17/i48/5246.htm
DOI: https://dx.doi.org/10.3748/wjg.v17.i48.5246