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©2011 Baishideng Publishing Group Co.
World J Gastroenterol. Dec 28, 2011; 17(48): 5246-5259
Published online Dec 28, 2011. doi: 10.3748/wjg.v17.i48.5246
Published online Dec 28, 2011. doi: 10.3748/wjg.v17.i48.5246
Table 2 Predicted future developments in the genetics of Crohn’s disease
What lies ahead in the genetics of crohn’s disease |
Gene-to-gene crosstalk and epistasis |
Genome-wide association studies |
Microarrays |
Fine single nucleotide polymorphism analysis |
Genetic consortium studies and genome-wide scans |
Genome-wide association studies |
Genetic consortium studies |
Future perspectives |
Functional studies to understand the mechanisms |
Combining genetic data with functional data |
Combination of a panel of clinical, biochemical, serological and genetic factors |
Functional consequences of polymorphisms |
Molecular and cellular mechanisms leading to Crohn’s disease |
Predict disease outcomes |
Redesigning the methods of treatment |
- Citation: Tsianos EV, Katsanos KH, Tsianos VE. Role of genetics in the diagnosis and prognosis of Crohn's disease. World J Gastroenterol 2011; 17(48): 5246-5259
- URL: https://www.wjgnet.com/1007-9327/full/v17/i48/5246.htm
- DOI: https://dx.doi.org/10.3748/wjg.v17.i48.5246