Vitamin D supplementation improves sustained virologic response in chronic hepatitis C (genotype 1)-naïve patients

Table 1 Baseline demographic, clinical and virologic characteristics of all patients

Baseline demographics	Peg/RBV (n = 36)	Peg/RBV + Vit D (n = 36)	P value
Age (yr)	49 ± 7	47 ± 11	0.123
Males (%)	60	50	0.015
Body mass index (kg/m2)	24 ± 3	27 ± 4	0.014
HCV genotype: 1a/1b (n)	3/33	3/33	0.138
Baseline HCV-RNA (log IU/mL)	6.2 ± 0.8	6.1 ± 0.7	0.126
High viral load	15 (42%)	18 (50%)	0.033
HCV-RNA > 800  000 IU/mL
Baseline ALT (U/L)	56 ± 31	55 ± 28	0.587
Advanced fibrosis (> F2)	7 (19%)	15 (42%)	0.001
Ethnicity (Russian /Jewish/Arab)	28/6/2	29/3/4	0.194

Peg/RBV: Pegylated interferon α and ribavirin; Vit D: Vitamin D; ALT: Alanine aminotransferase; HCV: Hepatitis C virus.