Increased fibrosis progression rates in hepatitis C patients carrying the prothrombin G20210A mutation

Table 1 Patient characteristics by fibrosis rates (by Poynard)

	Slow fibrosers	Fast fibrosers	P value
	(n = 116)	(n = 52)
Female (%)	37%	31%	0.43
Age (yr)	49.8 ± 10.5	43.9 ± 7.1	< 0.001
Age at infection (yr)	25.1 ± 10.8	25.2 ± 7.7	0.97
Infection duration (yr)	24.7 ± 8	18.7 ± 8.1	< 0.001
Alcohol intake ≥ 50 g/d	7.1%	10.4%	0.53
BMI (kg/m2)	23.8 ± 2.9	23.4 ± 3.1	0.5
Genotype (%)			0.49
1	74.3%	62.8%
2	2.8%	2.3%
3	16.5%	23.3%
4	6.4%	11.6%
Inflammatory score, grade (units)	1.3 ± 0.68	1.81 ± 0.69	< 0.001
Fibrosis stage (%)			< 0.001
0	14.7%	0%
1	45.7%	9.6%
2	29.3%	5.8%
3	8.6%	48.1%
4	1.7%	36.5%

BMI: Body mass index.