Review of dynamic contrast-enhanced ultrasound guidance in ablation therapy for hepatocellular carcinoma

Table 1 Treatment sessions of percutaneous ablation guided by contrast-enhanced ultrasound for hepatocellular carcinoma

Author[Ref.]	Year	Procedure	n	Contrast agent	Tumor size (mean, cm)	Treatment sessions (mean)
Numata et al[45]	2003	PEI, RFA	9	Levovist	1.4	ND
Minami et al[12]	2004	RFA	21	Levovist	1.7	1.05
Solbiati et al[46]	2004	RFA	51	SonoVue	ND	ND
Numata et al[47]	2008	RFA	15	Sonazoid	ND	1.04
Maruyama et al[48]	2009	PEI, RFA	42	Sonazoid	1.3	ND
Miyamoto et al[49]	2009	RFA	52	Sonazoid	ND	1.04
Minami et al[50]	2010	RFA	108	Sonazoid	1.7	1.1
Masuzaki et al[36]	2010	RFA	291	Sonazoid	1.6	1.33

HCC: Hepatocellular carcinoma; ND: Not described; PEI: Percutaneous ethanol injection; RFA: Radiofrequency ablation.