Inhibition of tumor angiogenesis by TTF1 from extract of herbal medicine

Figure 4 Microvessels in tumor tissue angiogenesis in HepG-2-transplanted nude mice. Brown staining indicates CD34 positive cells. A: Control, HepG-2-transplanted nude mouse treated with normal saline; B: TTF1, HepG-2-transplanted nude mouse treated with TTF1; C: Different doses of compound were used as treatments in the HepG-2-transplanted nude mice as follows: sTTF1 (5 μmol/kg); mTTF1 (10 μmol/kg); lTTF1 (20 μmol/kg); apigenin (40 μmol/kg); and Con (control group treated with normal saline). ^aP < 0.05, ^bP < 0.01 vs control group.