Serum manganese superoxide dismutase and thioredoxin are potential prognostic markers for hepatitis C virus-related hepatocellular carcinoma

Table 1 Patient clinical characteristics

Characteristics	Non-HCC group(n = 34)	HCC group(n = 30)	P value1
Age (yr)	62.3 ± 11.0	72.2 ± 7.5	< 0.001
Sex (male/female)	10/24	21/9	< 0.01
Plt (× 104/μL)	17.0 ± 5.5	10.3 ± 5.2	< 0.001
PT (%)	99.7 ± 13.3	77.6 ± 11.8	< 0.001
Alb (g/dL)	4.3 ± 0.4	3.6 ± 0.6	< 0.001
T-Bil (mg/dL)	0.8 ± 0.3	1.5 ± 0.8	< 0.001
ALT (IU/L)	44.8 ± 30.2	52.0 ± 28.2	0.12
γ-GTP (IU/L)	31.3 ± 16.1	56.2 ± 44.3	< 0.01
AFP (ng/mL)	7.2 ± 22.8	85.9 ± 197.6	< 0.001
DCP (mAU/mL)	22.8 ± 14.7	485.5 ± 1982.6	0.001
HCV serotype group (1/2)	18/10 (n = 28)	21/3 (n = 24)	0.06
HCV RNA level (high/low)	28/5 (n = 33)	21/4 (n = 25)	0.99

Data are shown as the mean ± SD. n: Number of patients or the number of samples analyzed.

¹Differences between mean values were evaluated using either the Fischer’s exact test or the Mann-Whitney U test, as appropriate. Plt: Platelet count; PT: Prothrombin time; Alb: Albumin; T-Bil: Total bilirubin; ALT: Alanine aminotransferase; γ-GTP: γ-glutamyl transpeptidase; AFP: alpha-fetoprotein; DCP: des-γ-carboxy prothrombin; HCV: Hepatitis C virus; RNA: Ribonucleic acid.