A special recurrent pattern in small hepatocellular carcinoma after treatment: Bile duct tumor thrombus formation

Table 1 Clinicopathologic characteristics of six cases of small hepatocellular carcinoma at the initial diagnosis

	Case 1	Case 2	Case 3	Case 4	Case 5	Case 6
Sex/age (yr)	M/35	M/57	M/45	M/50	M/38	M/41
Chief complaint	Epigastric pain	Asymptomatic	Asymptomatic	Epigastric pain	Asymptomatic	Epigastric pain
HBsAg/HCV-Ab	+/-	+/-	+/-	+/-	+/-	-/-
Liver cirrhosis	+	+	+	+	+	-
AFP (ng/mL)	203.5	25	283	226.1	578.3	725.3
sHCC location/size	VIII/2.7 cm	V/2.0 cm	VI/1.5 cm	IV/2.0 cm	V/1.6 cm	VI/2.6 cm
Treatment	Partial segments V and VIII resection	Partial segment V resection	RF	Left lobectomy	Partial segment V resection	Segments VI and VII resection
Resection state	R1	R1	Ablative margin less than 5 mm	R1	R1	R1
Histologic differentiation	Moderate	Moderate	Moderate	Poor	Poor	Poor
Vascular infiltration	-	-		-	-	+
Tumor microsatellites	-	-		-	-	-
Bile duct or canaliculus invasion	-	-		-	-	-
Capsule presence	-	+		+	+	-

+: Positive; -: Negative. sHCC: Small hepatocellular carcinoma; HBsAg: Hepatitis B surface antigen; HCV-Ab: Hepatitis C antibody.