Autophagy-related proteins Beclin-1 and LC3 predict cetuximab efficacy in advanced colorectal cancer

doi:10.3748/wjg.v17.i43.4779

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Nov 21, 2011 (publication date) through Nov 22, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Nov 21, 2011; 17(43): 4779-4786
Published online Nov 21, 2011. doi: 10.3748/wjg.v17.i43.4779

Table 4 Objective response rate and disease control rate of patients with wild type KRAS and KRAS mutation in cetuximab-containing chemotherapy group n (%)

Effect	Wild type KRAS	Mutant type KRAS	Total
CR	0 (0)	0 (0)	0
PR	11 (42.3)	1 (9.1)	12 (32.4)
SD	8 (30.8)	3 (27.3)	11 (29.7)
PD	7 (26.9)	7 (63.6)	14 (37.8)
Total	26 (70.3)	11 (29.7)	37 (100)

CR: Complete response; PR: Partial response; SD: Stable disease; PD: Progression disease.

Citation: Guo GF, Jiang WQ, Zhang B, Cai YC, Xu RH, Chen XX, Wang F, Xia LP. Autophagy-related proteins Beclin-1 and LC3 predict cetuximab efficacy in advanced colorectal cancer. World J Gastroenterol 2011; 17(43): 4779-4786
URL: https://www.wjgnet.com/1007-9327/full/v17/i43/4779.htm
DOI: https://dx.doi.org/10.3748/wjg.v17.i43.4779