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World J Gastroenterol. Oct 28, 2011; 17(40): 4509-4516
Published online Oct 28, 2011. doi: 10.3748/wjg.v17.i40.4509
Published online Oct 28, 2011. doi: 10.3748/wjg.v17.i40.4509
Table 2 Demographic, clinical and endoscopic characteristics of all patients with bleeding from peptic ulcers after consumption of nonsteroidal anti-inflammatory drugs, grouped according to whether they did or did not have Helicobacter pylori infection n (%)
Patients(n = 80) | Helicobacter pylori negative(n = 36) | Helicobacter pylori positive(n = 44) | P-value | |
Males | 61 (76.3) | 28 (77.8) | 33 (75.0) | 0.771 |
Age (yr) (mean ± SD) | 61.2 ± 15.9 | 60.6 ± 18.3 | 61.7 ± 13.9 | 0.767 |
Smoker | 0.703 | |||
Non-smoker | 43 (53.8) | 21 (58.3) | 22 (50.0) | |
Current | 26 (32.5) | 10 (27.8) | 16 (36.4) | |
Ex-smoker | 11 (13.8) | 5 (13.9) | 6 (13.6) | |
Symptoms on presentation | 0.721 | |||
Hematemesis | 11 (13.8) | 4 (11.1) | 7 (15.9) | |
Melena | 58 (72.5) | 26 (72.2) | 32 (72.7) | |
Hematemesis and melena | 11 (13.8) | 6 (16.7) | 5 (11.4) | |
Initial mean hemoglobin (g/dL) | 9.2 ± 2.3 | 8.7 ± 2.2 | 9.6 ± 2.4 | 0.076 |
American Society of Anesthesiology class | 0.600 | |||
1-2 | 62 (77.5) | 26 (72.2) | 36 (81.8) | |
3 | 15 (18.8) | 8 (22.2) | 7 (15.9) | |
4 | 3 (3.8) | 2 (5.6) | 1 (2.3) | |
Complete Rockall score | 0.183 | |||
0-2 | 39 (48.8) | 19 (52.8) | 20 (45.5) | |
3-5 | 34 (42.5) | 12 (33.3) | 22 (50) | |
6-8 | 7 (8.8) | 5 (13.9) | 2 (4.5) | |
1Comorbidity | 27 (33.8) | 12 (33.3) | 15 (34.1) | 0.943 |
Occasional consumption of NSAIDs | 47 (58.8) | 19 (52.8) | 28 (63.6) | 0.326 |
Patients on chronic LD ASA | 33 (41.3) | 17 (47.2) | 16 (36.4) | 0.326 |
Other antiplatelet drugs | 5 (6.3) | 2 (5.6) | 3 (6.8) | 0.999 |
Anticoagulants | 2 (2.5) | 2 (5.6) | 0 (0) | 0.199 |
Other drugs | 39 (48.8) | 15 (41.7) | 24 (54.5) | 0.252 |
Locations of ulcers | 0.515 | |||
Duodenum alone | 41 (51.3) | 21 (58.3) | 20 (45.5) | |
Stomach alone | 29 (36.3) | 11 (30.6) | 18 (40.9) | |
Stomach and duodenum | 10 (12.5) | 4 (11.1) | 6 (13.6) | |
Forrest | 0.684 | |||
1a | 2 (2.5) | 1 (2.8) | 1 (2.3) | |
1b | 12 (15.0) | 6 (16.7) | 6 (13.6) | |
2a | 4 (5.0) | 1 (2.8) | 3 (6.8) | |
2b | 3 (3.8) | 1 (2.8) | 2 (4.6) | |
2c | 16 (20.0) | 10 (27.8) | 6 (13.6) | |
3 | 43 (53.8) | 17 (47.2) | 26 (59.1) |
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Citation: Manguso F, Riccio E, de Nucci G, Aiezza ML, Amato G, Degl’Innocenti L, Piccirillo MM, De Dominicis G, Santoro T, Trimarco E, Balzano A.
Helicobacter pylori infection in bleeding peptic ulcer patients after non-steroidal antiinflammatory drug consumption. World J Gastroenterol 2011; 17(40): 4509-4516 - URL: https://www.wjgnet.com/1007-9327/full/v17/i40/4509.htm
- DOI: https://dx.doi.org/10.3748/wjg.v17.i40.4509