Evaluation of Cladribine treatment in refractory celiac disease type II

Table 2 The 1- and 2-yr response rates and the median time to response in the pre-treated (I) and the upfront 2-CdA (II) group

	Treatment(n)		Response (%)		Time to a 50% response rate (mo)
			12 mo	24 mo
Histological response	Group I	10	13	25	36
	Group II	22	20	58	24
	Overall	32	10	47	36 (3-96)
Immunological1 response	Group I	10	11	11	> 60
	Group II	22	52	58	12
	Overall	32	39	41	41 (2-96)
Clinical2 response	Group I	10	67	67	6
	Group II	22	95	95	3
	Overall	32	81	81	3 (2-72)
Overall response	Group I	10	22	38	36
	Group II	22	28	43	30
	Overall	32	25	41	36

¹P = 0.030 and

²P = 0.058 between group I and II.