Association between EGF +61A/G polymorphism and gastric cancer in Caucasians

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Jan 28, 2011 (publication date) through Nov 4, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Jan 28, 2011; 17(4): 488-492
Published online Jan 28, 2011. doi: 10.3748/wjg.v17.i4.488

Table 1 Associations between EGF +61A/G variants and clinicopathological parameters in patients with gastric lesions¹n (%)

	Cases	Controls	OR (95% CI)	P
Gastric lesions¹ (n = 207)
Genotypes
GG	38 (18.4)	231 (23.5)	1
GA	104 (50.2)	449 (45.6)	1.41 (0.92-2.15)	0.096
AA	65 (31.4)	304 (30.9)	1.30 (0.82-2.06)	0.237
GA + AA	169 (68.6)	753 (76.5)	1.36 (0.92-2.04)	0.109
Atrophy or intestinal metaplasia (n = 45)
Genotypes
GG	9 (20.0)	231 (23.5)	1
GA	20 (44.4)	449 (45.6)	1.44 (0.49-2.76)	0.743
AA	16 (35.6)	304 (30.9)	1.35 (0.55-3.37)	0.478
GA + AA	36 (80.0)	753 (76.5)	1.23 (0.56-2.78)	0.590
Gastric adenocarcinoma (n = 162)
Genotypes
GG	29 (17.9)	231 (23.5)	1
GA	84 (51.9)	449 (45.6)	1.49 (0.93-2.40)	0.082
AA	49 (30.2)	304 (30.9)	1.28 (0.77-2.16)	0.317
GA + AA	133 (82.1)	753 (76.5)	1.41 (0.90-2.21)	0.116

¹Gastric lesions: atrophy or intestinal metaplasia and gastric adenocarcinoma. OR: Odds ratios; CI: Confidence intervals.

Citation: Araújo AP, Costa BM, Pinto-Correia AL, Fragoso M, Ferreira P, Dinis-Ribeiro M, Costa S, Reis RM, Medeiros R. Association between EGF +61A/G polymorphism and gastric cancer in Caucasians. World J Gastroenterol 2011; 17(4): 488-492
URL: https://www.wjgnet.com/1007-9327/full/v17/i4/488.htm
DOI: https://dx.doi.org/10.3748/wjg.v17.i4.488