Nitric oxide-releasing aspirin but not conventional aspirin improves healing of experimental colitis

Figure 8 The weight of colonic tissue and alterations in colonic blood flow on day 10 after induction of trinitrobenzenesulfonic acid colitis in rats treated with aspirin or celecoxib with or without 16, 16 dm prostaglandin E₂ (5 μg/kg per day ig). Mean ± SE of 6-8 rats. ^aP < 0.02 vs vehicle (control); ^cP < 0.05 vs vehicle (control) and aspirin (ASA) groups; ^eP < 0.05 vs ASA and celecoxib groups without concurrent prostaglandin E₂ (PGE₂) administration. TNBS: Trinitrobenzenesulfonic acid; CBF: Colonic blood flow.