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©2011 Baishideng Publishing Group Co.
World J Gastroenterol. Sep 28, 2011; 17(36): 4113-4117
Published online Sep 28, 2011. doi: 10.3748/wjg.v17.i36.4113
Published online Sep 28, 2011. doi: 10.3748/wjg.v17.i36.4113
Table 3 Relationship between -765 G/C COX-2 polymorphism and clinical data of patients with pancreatic cancer n (%)
| Group | G+ allele(GC and GG)(n = 47) | P value | G- allele(CC)(n = 38) | P value | |
| Age | < 65 | 23 (48.9) | NS | 16 (42.1) | NS |
| ≥ 65 | 24 (51.1) | 22 (57.9) | |||
| Gender | Male | 22 (46.8) | NS | 19 (50.0) | NS |
| Female | 25 (53.2) | 19 (50.0) | |||
| Tumor size | ≤ 3 cm | 17 (40.4) | NS | 15 (39.5) | NS |
| > 3 cm | 28 (59.6) | 23 (60.5) | |||
| Tumor | G1 + G2 | 27 (57.4) | NS | 21 (55.3) | NS |
| Differentiation | G3 | 20 (40.4) | 16 (42.1) | ||
| Lymph node | Absent | 28 (59.8) | NS | 18 (47.4) | NS |
| Metastases | Present | 19 (40.4) | 20 (52.6) | ||
| Weight loss | < 10 % | 30 (63.8) | NS | 21 (55.3) | NS |
| ≥ 10% | 17 (36.2) | 17 (44.7) | |||
| Smoking | Yes | 23 (48.9) | NS | 17 (44.7) | NS |
| No | 24 (51.1) | 21 (55.3) | |||
| CA19-9 | < 37 U/mL | 12 (25.5) | NS | 12 (31.6) | NS |
| ≥ 37 U/mL | 35 (74.5) | 26 (68.4) |
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Citation: Talar-Wojnarowska R, Gasiorowska A, Olakowski M, Lampe P, Smolarz B, Romanowicz-Makowska H, Malecka-Panas E. Role of
cyclooxygenase-2 gene polymorphisms in pancreatic carcinogenesis. World J Gastroenterol 2011; 17(36): 4113-4117 - URL: https://www.wjgnet.com/1007-9327/full/v17/i36/4113.htm
- DOI: https://dx.doi.org/10.3748/wjg.v17.i36.4113