Prognostic significance of erythropoietin and erythropoietin receptor in gastric adenocarcinoma

Figure 1 Erythropoietin, erythropoietin receptor, vascular endothelial growth factor and CD34 expression in biopsies from gastric adenocarcinoma patients. A, B: Erythropoietin and erythropoietin receptor positive immunostaining signals were localized in the cytoplasm of tumor cells with a scattered distribution pattern in most cases; C: Vascular endothelial growth factor immunoreactivity was detected in the cytoplasm of gastric adenocarcinoma. Original magnification: × 200; D: Microvessels in tumor were highlighted by staining endothelial cells for anti-CD34. Any brown-staining endothelial cell or cell cluster that was clearly separated from adjacent microvessels was considered as a single, countable microvessel. Original magnification: × 100.