Preclinical evaluation of azathioprine plus buthionine sulfoximine in the treatment of human hepatocarcinoma and colon carcinoma

doi:10.3748/wjg.v17.i34.3899

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Sep 14, 2011 (publication date) through Nov 29, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Sep 14, 2011; 17(34): 3899-3911
Published online Sep 14, 2011. doi: 10.3748/wjg.v17.i34.3899

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Figure 8 Time course of the events in our molecular model. AZA: Azathioprine; GST: Glutathione-S-transferase; GSH: Glutathione; GCS: γ-glutamylcysteine synthetase; BSO: Buthionine sulfoximine; NAC: N-acetylcysteine; PARP: Poly (ADP-ribose) polymerase; LDH: Lactate dehydrogenase.

Citation: Hernández-Breijo B, Monserrat J, Ramírez-Rubio S, Cuevas EP, Vara D, Díaz-Laviada I, Fernández-Moreno MD, Román ID, Gisbert JP, Guijarro LG. Preclinical evaluation of azathioprine plus buthionine sulfoximine in the treatment of human hepatocarcinoma and colon carcinoma. World J Gastroenterol 2011; 17(34): 3899-3911
URL: https://www.wjgnet.com/1007-9327/full/v17/i34/3899.htm
DOI: https://dx.doi.org/10.3748/wjg.v17.i34.3899