Interleukin-10 gene polymorphisms and hepatocellular carcinoma susceptibility: A meta-analysis

Table 3 Pooled odds ratio for Interleukin-10 gene polymorphism and hepatocellular carcinoma susceptibility in meta-analyses

Comparison	No. of study	OR (95% CI)	P-Publication bias			Heterogeneity test2
			P1value	Egger3	Begg4	P value	I2
IL-10-1082
AA vs AG + GG	6	1.11 (0.90, 1.37)	0.32	0.004	0.02	0.44	0
IL-10-592
CC vs AA + AC	4	1.68 (1.25, 2.26)	0.001	0.43	1	0.11	50.80%
C allele vs A allele	4	1.29 (1.12, 1.49)	0.001	0.51	0.73	0.86	0
IL-10-819
TT vs TC + CC	3	1.02 (0.79, 1.32)	0.88	0.13	0.3	0.14	48.90%

¹Fixed effects models were used, weighted by the inverse variance. All statistical tests are two sided;

²P < 0.1 is considered statistically significant for Q statistics; I² is interpreted as the proportion of total variation contributed by between-study variation;

³Egger’s test to evaluate publication bias, P < 0.05 is considered statistically significant;

⁴Begg’s test to evaluate publication bias, P < 0.05 is considered statistically significant. OR: Odds ratio.