Interleukin-10 gene polymorphisms and hepatocellular carcinoma susceptibility: A meta-analysis

Table 2 Interleukin-10 gene polymorphism and hepatocellular carcinoma susceptibility

Gene	Polymorphism	HCC group genotype1			Control group genotype2			HWE	Ref.
		AA	AG	GG	AA	AG	GG
IL-10	-1082 G/A	39	79	-	67	147	-	Yes	[24]
IL-10	-1082 G/A	24	24	10	56	68	21	Yes	[23]
IL-10	-1082 G/A	42	5	1	176	10	2	No	[26]
IL-10	-1082 G/A	130	119	-	115	135	-	Yes	[27]
IL-10	-1082 G/A	86	12	0	160	15	0	Yes	[28]
IL-10	-1082 G/A	201	28	1	675	112	5	Yes	[29]
		AA	AC	CC	AA	AC	CC
IL-10	-592 C/A	93	84	31	259	223	46	Yes	[25]
IL-10	-592 C/A	17	23	8	85	78	25	Yes	[26]
IL-10	-592 C/A	89	101	26	384	299	65	Yes	[29]
IL-10	-592 C/A	49	38	11	95	60	19	Yes	[28]
		TT	TC	CC	TT	TC	CC
IL-10	-819 T/C	17	23	8	85	78	25	Yes	[26]
IL-10	-819 T/C	130	119	-	115	135	-	Yes	[27]
IL-10	-819 T/C	49	38	11	95	60	19	Yes	[28]

¹Absolute number of patients;

²Absolute number of controls; OR: Odds ratio; HCC: Hepatocellular carcinoma; HWE: Hardy-Weinberg equilibrium.