RNAi knockdown of PIK3CA preferentially inhibits invasion of mutant PIK3CA cells

Figure 4 PIK3CA-siRNA reduced migration of BGC-823 and HGC-27 cells using an in vitro wound healing assay. A: The results were expressed as average gap and compared with the two control groups. The distance of the wound was measured at five reference points along the scratch wound. ^aP < 0.05 vs controls, ^bP < 0.01 vs controls, n = 3; B: A representative result of cell migration at 0 h and 24 h (original magnification, × 150). Con: Control group; Neg: Negative control group; Exp: Experimental group.