Repeated anastomotic recurrence of colorectal tumors: Genetic analysis of two cases

Table 1 Microsatellite markers used in the loss of heterozygosity study, with relevant cytogenetic locations, putative genes involved and their function, and references to papers describing a role for colonic carcinogenesis

Microsatellite Markers	Cytogenetic band	Gene	Function	Ref.
BAT40	1p13.1			[8]
MYC-L	1p34			[8]
BAT 26	2p16.3	hMSH2	Mismatch repair enzyme	[8]
D2S123	2p16			[8]
D3S1481	3p14	FHIT	Histidine triad gene family (purine metabolism)	[9]
D4S2397	4p15.2			[10]
D5S346	5q21	APC	Antagonist of the Wnt signaling pathway	[8]
D10S1671	10q25
D10S169	10q26.3	MGMT	DNA defense vs O6-methylguanine	[11]
D10S1765	10q23.3	PTEN	Protein tyrosine phosphatase	[12]
D16S421	16q22	CDH1	Ca++ dependent cell-cell adhesion glycoprotein
D16S402	16q23-q24
D16S507	16q23.2
D17S250	17q21			[8]
TP53ALU	17p13.1	TP53	Tumor protein “guardian of the genome”
TP53	17p13	TP53	Tumor protein “guardian of the genome”	[13]
D18S452	18p11.23			[14]
D18S53	18p11.22-p11			[13]
D18S64	18q21	DCC	Receptor for netrin 1	[15]
D18S857	18q22.1	DCC	Receptor for netrin 1
DXYS233	Xp22.32-Yp11.3			[16]
SHOX	Xp22.3			[16]
DXYS154	Xqter-Yqter			[16]
DXS8009	Xq25-q26
DXS8098	Xq24-q25