Overexpression of TLR3, TLR4, TLR7 and TLR9 in esophageal squamous cell carcinoma

Table 4 Analysis of the relationship between the expression of Toll-like receptors in each cellular type with the clinicopathologic characteristics of esophageal squamous cell carcinoma n (%)

Factors	Tumor Grade			Depth of invasion		LN metastasis
	W	M	P	≤muscularis	≥adventitia	Negative	Positive
Number of cases	30	29	28	37	50	34	53
TLR4 MICs (+)	19 (63.3)	16 (55.2)	12(42.9)	12(32.4)	35(70)	14(41.2)	33(62.3)
P	0.245			0.001		0.018
TLR9 fibroblast (+)	20 (66.7)	18 (62.1)	17(60.7)	30(81.1)	23(43.4)	29(85.3)	24(45.3)
P	0.885			0.001		0.006

All values are presented as the number of cases, with percentages in parentheses. TLR: Toll-like receptor; LN: Lymph node; MICs: Mononuclear inflammatory cells; W: Well differentiated; M: Moderately differentiated; P: Poorly differentiated.