Characteristics and outcomes of acute upper gastrointestinal bleeding after therapeutic endoscopy in the elderly

doi:10.3748/wjg.v17.i32.3724

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Aug 28, 2011 (publication date) through Jan 5, 2025

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Aug 28, 2011; 17(32): 3724-3732
Published online Aug 28, 2011. doi: 10.3748/wjg.v17.i32.3724

Table 1 Characteristics of patients for the entire group and for each cohort

	Total	Patients aged≥65 yr	Patients aged < 65 yr	P value
	(n = 526)	(n = 235)	(n = 291)	P value
Age (yr)	60 ± 15.9	74.2 ± 6.7	48.4 ± 11.1	< 0.001
Male: n (%)	370 (70)	148 (63)	222 (76)	< 0.001
Presenting symptoms: ¹n (%)
Hematemesis	207 (39)	65 (28)	142 (49)	< 0.001
Melena	214 (41)	126 (53)	88 (30)	< 0.001
“Coffee ground” vomiting	86 (16)	36 (15)	50 (17)	0.57
Hematochezia	19 (4)	8 (4)	11 (4)	0.82
Clinical findings: n (%)
Red blood on nasogastric lavage	97 (18)	41 (17)	56 (19)	0.60
Systolic blood pressure < 100 mmHg	163 (31)	62 (26)	101 (35)	0.04
Heart rate > 100 beats/min	192 (37)	63 (27)	129 (44)	< 0.001
Presence of hemodynamic instability	313 (60)	114 (49)	199 (68)	< 0.001
Comorbid illness: ¹n (%)
Cardiovascular disease	109 (21)	81 (34)	28 (10)	< 0.001
Cerebrovascular disease	49 (9)	34 (14)	15 (5)	< 0.001
Chronic renal failure	37 (7)	17 (7)	20 (7)	0.87
Liver cirrhosis	140 (27)	45 (19)	95 (33)	< 0.001
Cancer	64 (12)	33 (14)	31 (11)	0.24
Diabetes mellitus	126 (24)	87 (37)	39 (1)	< 0.001
Hypertension	186 (35)	125 (53)	61 (21)	< 0.001
Alcohol drinking: n (%)	246 (47)	66 (28)	180 (62)	< 0.001
Previous use of medications: ¹n (%)
Low-dose aspirin	111 (21)	82 (35)	29 (10)	< 0.001
Clopidogrel	33 (6)	30 (13)	3 (1)	< 0.001
Warfarin	38 (7)	22 (9)	16 (6)	0.09
NSAID other than aspirin	123 (23)	57 (24)	66 (23)	0.67
Laboratory features at presentation:
Hemoglobin (g/dL)	8.7 ± 4.7	8.4 ± 2.3	9.0 ± 6.0	0.19
White blood count (10³/μL)	11.8 ± 8.1	11.2 ± 5.3	12.3 ± 9.7	0.15
Platelets (10³/μL)	232 ± 125	242 ± 116	223 ± 131	0.09
Prothrombin time (s)	13.4 (11.4-248)	13.2 (11.4-160)	13.9 (11.4-248)	0.84
Creatinine (mg/dL)	1.1 (0.2-11.8)	1.3 (0.4-10.8)	0.9 (0.2-11.8)	0.44

Categorical variables are presented as number and percentage, and continuous variables are presented as the mean ± SD or median and range when appropriate.

¹Some patients presented with more than 1 symptom or comorbid illness and used more than 1 drug. NSAID: Non-steroidal anti-inflammatory drug.

Citation: Charatcharoenwitthaya P, Pausawasdi N, Laosanguaneak N, Bubthamala J, Tanwandee T, Leelakusolvong S. Characteristics and outcomes of acute upper gastrointestinal bleeding after therapeutic endoscopy in the elderly. World J Gastroenterol 2011; 17(32): 3724-3732
URL: https://www.wjgnet.com/1007-9327/full/v17/i32/3724.htm
DOI: https://dx.doi.org/10.3748/wjg.v17.i32.3724