A nested case-control study of maternal-neonatal transmission of hepatitis B virus in a Chinese population

Table 2 Determinants of perinatal transmission of hepatitis B virus (Hunan, China, 2005-2006)

Research factor	OR (95% CI)
	Single factors analysis	Adjust
Education of mother
< College	Reference	Reference
> College	0.50 (0.31-0.81)	1.17 (0.56-2.45)
Income (yuan/mo)
< 1500	Reference	Reference
> 1500	1.06 (0.65-1.73)	1.16 (0.72-1.87)
First-degree family history
No	Reference	Reference
Yes	3.28 (1.98-5.46)	2.84 (1.47-5.48)
Liver function
Normal	Reference	Reference
Abnormal	2.07 (1.17-3.65)	1.11 (0.48-2.55)
Systematic treatment
No	Reference	Reference
Yes	0.36 (0.21-0.66)	0.36 (0.17-0.76)
EHP
No	Reference	Reference
Yes	1.83 (0.74-4.52)	0.88 (0.28-2.75)
Intrahepatic cholestasis
No	Reference	Reference
Yes	2.40 (1.32-4.36)	2.71 (1.01-7.27)
Premature rupture of membranes
No	Reference	Reference
Yes	2.29 (1.28-4.10)	2.25 (1.08-4.68)
Anti-hepatitis B immunoglobulin
No	Reference	Reference
Yes	0.38 (0.23-0.62)	0.27 (0.12-0.59)
Fetal distress
No	Reference	Reference
Yes	1.95 (1.21-3.15)	1.70 (0.93-3.10)

OR: Odds ratios; CI: Confidence intervals; EHP: Edema hypertension proteinuria syndrome.