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©2011 Baishideng Publishing Group Co.
World J Gastroenterol. Aug 14, 2011; 17(30): 3526-3530
Published online Aug 14, 2011. doi: 10.3748/wjg.v17.i30.3526
Published online Aug 14, 2011. doi: 10.3748/wjg.v17.i30.3526
Table 5 Virological response in predicting ADV resistance at week 96
| Variables | Adefovir resistance | Sensitivity (%, 95% CI) | Specificity | Positive predictive value | Negative predictive value |
| n (%) | (%, 95% CI) | (%, 95% CI) | (%, 95% CI) | ||
| HBV DNA level ≥ 60 IU/mL at Week 12 (n = 59) | 12 (20) | 85 (56–97) | 25 (15–38) | 20 (11–33) | 89 (63-98) |
| HBV DNA level > 2000 IU/mL at Week 12 (n = 38) | 12 (32) | 85 (56–97) | 58 (45–70) | 31 (18–48) | 84 (81–99) |
| HBV DNA level ≥ 60 IU/mL at Week 24 (n = 51) | 12 (24) | 85 (56–97) | 38 (26-51) | 23 (13–38) | 92 (73–98) |
| HBV DNA level > 2000 IU/mL at Week 24 (n = 32) | 11 (34) | 78 (48–94) | 66 (53–77) | 34 (19–53) | 93 (80–98) |
| HBV DNA level ≥ 60 IU/mL at Week 48 (n = 43) | 12 (28) | 85 (56–97) | 51 (38–63) | 28 (16–44) | 72 (56–84) |
| HBV DNA level > 2000 IU/mL at Week 48 (n = 27) | 9 (33) | 64 (35–86) | 71 (58–81) | 33 (17–53) | 90 (77–96) |
- Citation: Sinn DH, Lee HI, Gwak GY, Choi MS, Koh KC, Paik SW, Yoo BC, Lee JH. Virological response to adefovir monotherapy and the risk of adefovir resistance. World J Gastroenterol 2011; 17(30): 3526-3530
- URL: https://www.wjgnet.com/1007-9327/full/v17/i30/3526.htm
- DOI: https://dx.doi.org/10.3748/wjg.v17.i30.3526