Prediction of nephrotoxicity induced by cisplatin combination chemotherapy in gastric cancer patients

Table 3 Acute renal failure (ARF) laboratory data¹ corresponding to renal status post-ARF²

			Renal status post-ARF		P value3
Variable	Normal range	Unit	Recovered (n = 33)	Unrecovered (n = 8)
Hb	14.0–16.7	g/dL	10.28 ± 1.62 (n = 31)	10.238 ± 1.30 (n = 8)	0.941
HT	14.7–50.7	%	29.52 ± 4.70 (n = 32)	29.93 ± 3.41 (n = 8)	0.820
Protein	6.3–8.3	g/dL	6.72 ± 0.78 (n = 24)	7.00 ± 0.95 (n = 3)	0.564
Albumin	3.5–5.0	g/dL	3.95 ± 0.61 (n = 24)	4.03 ± 0.65 (n = 3)	0.818
BUN	5–23	mg/dL	23.78 ± 13.60 (n = 33)	23.0 ± 4.87 (n = 8)	0.876
SCR	0.3-1.5	mg/dL	1.75 ± 0.48 (n = 33)	2.21 ± 0.61 (n = 8)	0.026
GFR	120-130	mL/min	43.30 ± 7.81 (n = 33)	36.0 ± 8.98 (n = 8)	0.026
Na	136–150	meg/L	136.60 ± 4.36 (n = 32)	137.63 ± 2.72 (n = 8)	0.529
Cl	98–110	meg/L	101.49 ± 6.59 (n = 24)	99.50 ± 2.65 (n = 4)	0.564
K	3.5–5.3	meg/L	4.22 ± 0.93 (n = 32)	4.46 ± 0.60 (n = 8)	0.491
P	3.0–4.5	mg/dL	4.13 ± 0.87 (n = 18)	3.93 ± 0.43 (n = 4)	0.659
Mg	1.6–2.6	mg/dL	1.83 ± 0.42 (n = 22)	1.833 ± 0.47 (n = 3)	0.995
Ca	8.0-10.0	mg/dL	9.06 ± 0.51 (n = 23)	9.40 ± 0.80 (n = 4)	0.269

¹Laboratory data were checked at the time at which the value of serum creatinine (SCR) was highest after increasing the SCR > 1.5 mg/dL. ²We divided 41 patients into two groups; recovered consisted of patients whose SCRs had decreased below 1.5 mg/dL after acute renal failure, unrecovered consisted of patients whose SCRs remained greater than 1.5 mg/dL.

³Unpaired Student’s t–test. BUN: Blood urea nitrogen; GFR: Glomerular filtration rate.