Liver function alterations after laparoscopy-assisted gastrectomy for gastric cancer and its clinical significance

Table 3 Comparison of alanine transaminase levels on the first postoperative day in patients who underwent a gastrectomy n (%)

Variables	Normal group (n = 80)	Elevated group (n = 135)	P value
Gender (M:F)	59:21	105:30	0.502
Age (yr, mean ± SD)	58.6 ± 13.4	58.6 ± 12.0	0.981
BMI (kg/m2, mean ± SD)	22.3 ± 3.3	24.4 ± 3.0	< 0.001
Underlying liver disease			0.153
No	70 (87.5)	114 (84.4)
Yes	10 (12.5)	21 (15.6)
Fatty liver	2 (2.5)	13 (9.7)
Hepatitis	8 (10.0)	8 (5.9)
Operation time (min, mean ± SD)	168.9 ± 61.4	206.7 ± 73.6	< 0.001
Types of operation			0.094
Open	52 (65.0)	72 (53.3)
Laparoscopy-assisted	28 (35.0)	63 (46.7)
Combined operation			0.093
No	58 (72.5)	111 (82.2)
Yes	22 (27.5)	24 (17.8)
Anesthetic agent			0.979
Sevoflurane	24 (30.0)	40 (29.6)
Desflurane	56 (70.0)	95 (70.4)
Intraoperative transfusion			0.894
No	71 (88.8)	119 (88.1)
Yes	9 (11.3)	16 (11.9)
Aberrant left hepatic artery			0.052
Absence or preservation	79 (98.8)	127 (94.1)
Artery ligation	1 (1.3)	8 (5.9)
Intraoperative hepatic injury			0.048
No	79 (98.8)	125 (92.6)
Yes	1 (1.3)	10 (7.4)
Mean ALT at POD1 (± SD)	28.2 ± 8.1	101.4 ± 97.1	< 0.001

BMI: Body mass index; POD: Postoperative day; ALT: Alanine aminotransferase.