Function of nonstructural 5A protein of genotype 2a in replication and infection of HCV with gene substitution

Figure 5 Comparison of cell culture-produced hepatitis C virus produced by chimera and prototype. The full-length RNA transcripts of the prototype and chimera were transfected into Huh-7.5 cells. The supernatants were harvested at the indicated time points after transfection. The infectivity titers of the supernatants were determined, and the values were presented as focus forming unit per milliliter (ffu/mL).