Influence of irritable bowel syndrome on treatment outcome in gastroesophageal reflux disease

Figure 3 Response rates for gastroesophageal reflux disease/erosive/non-erosive reflux disease patients with or without irritable bowel syndrome-like symptoms after 4 and 8 wk of treatment with pantoprazole. ^aP < 0.0001 irritable bowel syndrome (IBS)-like + vs IBS-like - in patients with gastroesophageal reflux disease (GERD) after 4 wk; ^bP < 0.0001 IBS-like + vs IBS-like - in patients with GERD after 8 wk, ^cP < 0.0001 IBS-like + vs IBS-like - in patients with erosive reflux disease (ERD) after 4 wk, ^dP = 0.0339 IBS-like + vs IBS-like - in patients with ERD after 8 wk, ^eP = 0.0088 IBS-like + vs IBS-like - in patients with non-erosive reflux disease (NERD) after 8 wk.