Brief Article
Copyright ©2011 Baishideng Publishing Group Co.
World J Gastroenterol. Jul 21, 2011; 17(27): 3248-3256
Published online Jul 21, 2011. doi: 10.3748/wjg.v17.i27.3248
Table 3 Subgroup analysis of the association between GSTM1 polymorphism and hepatocellular carcinoma risk
GroupNo. of studies (cases/controls)Statistical methodOR (95% CI)P
All studies19 (2660/4017)Random1.487 (1.159-1.908)0.002
Residence area of the subjects
High-incidence area11 (1510/2666)Random1.659 (1.264-2.177)0.000
Low-incidence area7 (1040/1239)Random1.235 (0.753-2.026)0.402
Mixed areas1 (110/112)-1.602 (0.943-2.721)0.081
No. of cases
< 1009 (651/1262)Random1.676 (1.061-2.649)0.027
≥ 10010 (2009/2755)Random1.365 (1.005-1.853)0.046
Source of controls
Population-based9 (1489/1548)Random1.316 (0.915-1.892)0.139
Hospital-based10 (1171/2469)Random1.675 (1.251-2.243)0.001