Influence of irritable bowel syndrome on treatment outcome in gastroesophageal reflux disease

Table 2 Pre-post differences of “acid complaints” and “lower abdominal complaints” in erosive and non-erosive reflux disease patients with and without irritable bowel syndrome-like symptoms after 4 and 8 wk

	ERD		NERD
	IBS-like +	IBS-like -	IBS-like +	IBS-like -
Acid complaints
4 wk	1.6	1.6	1.6	1.4
8 wk	1.6	1.7	1.7	1.6
Lower abdominal complaints
4 wk	0.7	0.7	1.0a	0.7
8 wk	1.0	0.8	1.2b	0.8

^aP = 0.049 irritable bowel syndrome (IBS)-like + vs IBS-like -;

^bP = 0.0092 IBS-like + vs IBS-like -. ERD/NERD: Erosive/non-erosive reflux disease.