Intestinal inflammation and colorectal cancer: A double-edged sword?

doi:10.3748/wjg.v17.i26.3092

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Jul 14, 2011 (publication date) through Sep 27, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Jul 14, 2011; 17(26): 3092-3100
Published online Jul 14, 2011. doi: 10.3748/wjg.v17.i26.3092

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Figure 2 Hypothetical relationship between inflammatory bowel disease and colitis associated colorectal cancer. The T helper (Th)2 immune response characterizing ulcerative colitis determines an elevated risk of developing colitis associated colorectal cancer (CAC). In Crohn's disease, while a Th17-mediated immune response could cause inflammation and enhance CAC risk, the shift towards a Th1-mediated colitis could lower the incidence of CAC.

Citation: Rizzo A, Pallone F, Monteleone G, Fantini MC. Intestinal inflammation and colorectal cancer: A double-edged sword? World J Gastroenterol 2011; 17(26): 3092-3100
URL: https://www.wjgnet.com/1007-9327/full/v17/i26/3092.htm
DOI: https://dx.doi.org/10.3748/wjg.v17.i26.3092