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©2011 Baishideng Publishing Group Co.
World J Gastroenterol. Jul 14, 2011; 17(26): 3092-3100
Published online Jul 14, 2011. doi: 10.3748/wjg.v17.i26.3092
Published online Jul 14, 2011. doi: 10.3748/wjg.v17.i26.3092
Figure 2 Hypothetical relationship between inflammatory bowel disease and colitis associated colorectal cancer.
The T helper (Th)2 immune response characterizing ulcerative colitis determines an elevated risk of developing colitis associated colorectal cancer (CAC). In Crohn's disease, while a Th17-mediated immune response could cause inflammation and enhance CAC risk, the shift towards a Th1-mediated colitis could lower the incidence of CAC.
- Citation: Rizzo A, Pallone F, Monteleone G, Fantini MC. Intestinal inflammation and colorectal cancer: A double-edged sword? World J Gastroenterol 2011; 17(26): 3092-3100
- URL: https://www.wjgnet.com/1007-9327/full/v17/i26/3092.htm
- DOI: https://dx.doi.org/10.3748/wjg.v17.i26.3092