Down-regulation of STAT3 expression by vector-based small interfering RNA inhibits pancreatic cancer growth

Figure 3 Effects of silence of signal transduction and activation of transcription 3 gene on apoptosis of pancreatic cancer cells. SW1990 cells and stably-transfected cells (SW1990-Con and SW1990-RNAi) were collected to analyze the cell apoptosis with flow cytometry. More apoptotic cells were detected in SW1990-RNAi cells than in parental SW1990 and SW1990-Con cells. Columns: mean (n = 3); bars: SD. ^aP < 0.05 vs control. SW1990-Con: SW1990 pRNAT-Con transfectants; SW1990-RNAi: SW1990 STAT3-RNAi transfectants.