T1-weighted dual-echo MRI for fat quantification in pediatric nonalcoholic fatty liver disease

doi:10.3748/wjg.v17.i25.3012

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Jul 7, 2011; 17(25): 3012-3019
Published online Jul 7, 2011. doi: 10.3748/wjg.v17.i25.3012

Table 1 Clinical and laboratory characteristics of children with and without nonalcoholic fatty liver disease

Characteristics	NAFLD (n = 25)	No NAFLD (n = 25)
BMI, kg/m²	28.4 (26.4-30.3)^a	25.6 (24.4-26.8)
BMI-Standard deviation score	2.20 (2.02-2.30)^a	2.01 (1.92-2.17)
Waist circumference, cm	96.9 (91.8-102.1)^b	85.2 (80.3-89.0)
Systolic BP, mmHg	117 (112-122)^b	107 (105-109)
Diastolic BP, mmHg	70 (67-74)^b	68 (65-70)
Aspartate aminotransferase, U/L	45 (33-58)^c	24 (20-28)
Alanine aminotransferase, U/L	73 (55-91)^c	21 (18-25)
γ-glutamyl transferase, U/L	31 (23-39)^c	13 (12-14)
Total cholesterol, mg/dL	162 (143-181)	168 (146-190)
HDL cholesterol, mg/dL	42 (38-49)	40 (37-43)
Triglycerides, mg/dL	161 (115-207)^b	112 (61-134)
Glucose, mmol/L	4.89 (4.69-5.10)	4.88 (4.77-5.02)
Insulin, μU/mL	31.2 (21.9-40.6)^a	20.1 (16.2-24.1)
HOMA-IR values	4.27 (3.40-5.10)^a	3.45 (2.97-4.01)
Hepatic fat fraction, %	19.0 (15.1-27.4)^c	2.0 (1.3-2.5)

Results are expressed as n (%), mean (95% CI), or geometric mean (95% CI) for log-transformed variables.

^aP < 0.05,

^bP < 0.01,

^cP < 0.0001. BMI: Body mass index; NAFLD: Nonalcoholic fatty liver disease; BP: Blood pressure; HDL: High density lipoprotein; HOMA-IR: Homeostasis model assessment of insulin resistance.

Citation: Pacifico L, Martino MD, Catalano C, Panebianco V, Bezzi M, Anania C, Chiesa C. T1-weighted dual-echo MRI for fat quantification in pediatric nonalcoholic fatty liver disease. World J Gastroenterol 2011; 17(25): 3012-3019
URL: https://www.wjgnet.com/1007-9327/full/v17/i25/3012.htm
DOI: https://dx.doi.org/10.3748/wjg.v17.i25.3012