α-fetoprotein involvement during glucocorticoid-induced precocious maturation in rat colon

Figure 5 α-fetoprotein expressions in 8-d-old rat colons treated with or without hydrocortisone, hydrocortisone + mifepristone and mifepristone alone. α-fetoprotein (AFP) expression was determined by the Western blotting using AFP polyclonal antibody (A), and results indicated are in percentage above the β-actin value and are representative of three independent experiments (B). Each data point (± SD; bars) is the mean of four independent trials. C: Pups received saline; HC: Pups received hydrocortisone; HC+M: Pups treated with both hydrocortisone and mifepristone; M: Pups treated with mifepristone only. ^aP < 0.05 vs control animals; ^dP < 0.01 vs hydrocortisone-treated animals.