Characterization of a novel rat cholangiocarcinoma cell culture model-CGCCA

Figure 2 The tumors formed at the cell transplantation site of the CCA xenograft with central necrosis in all large tumors suggesting the fast growth of this malignant tumor at the thigh of the nude mice had a latency period of 4-6 wk and, as represented by (A) gross picture, (B) the photomicrographs of the necropsy, (C) histology, and (D) autoradiography (D). Of note, all tumor cells excluding necrosis tissue possessed high 2-Deoxy-2-(¹⁸F)fluoro-D-glucose uptake.