Molecular biology of pancreatic cancer

Table 1 Pancreatic cancer risk factors

Factor	Type	Group	Maximum risk to average ratio
Smoking	Exogenous	Behavioral	3
Alcohol	Exogenous	Behavioral	Non-significant
Diet/obesity	Exogenous	Behavioral	1.72
Occupational hazard	Exogenous	Environmental	-
Radiation	Exogenous	Environmental	Inconclusive
Age	Endogenous	Biological	-
Race	Endogenous	Biological/behavioral/environmental	1.4
Family history	Endogenous	Genetic	32
Peutz-Jeghers syndrome	Endogenous	Genetic	132
FAMMM syndrome	Endogenous	Genetic	13.1
HNPCC	Endogenous	Genetic	7
Hereditary pancreatitis	Endogenous	Genetic	60
Chronic pancreatitis	Endogenous	Behavioral	26.3
Diabetes mellitus	Endogenous	Biological/environmental	2.0
Hormonal	Endogenous	Biological	Inconclusive
Allergy	Endogenous	Biological	Non-significant

FAMMM: Familial atypical multiple mole melanoma; HNPCC: Hereditary non-polyposis colorectal carcinoma syndrome.