Association between ITGA2 C807T polymorphism and gastric cancer risk

Table 3 Stratified analyses for variant ITGA2 genotypes in cases and controls n (%)

Variable	(CT + TT)/CC		Crude OR (95% CI)	P value	Adjusted OR1 (95% CI)	P value
	Cases	Controls
Age (yr), (median)
≤ 58	81 (26.4)/68 (22.1)	80 (26)/85 (27.7)	1.27 (0.81-1.97)	0.298	1.31 (0.83-2.06)	0.247
> 58	85 (27.7)/73 (23.8)	57 (18.6)/85 (27.7)	1.74 (1.10-2.75)	0.018	1.88 (1.17-3.03)	0.010
Sex
Females	45 (14.7)/31 (10.1)	38 (12.4)/38 (12.4)	1.45 (0.76-2.76)	0.255	1.52 (0.73-2.93)	0.206
Males	110 (35.8)/121 (39.4)	99 (32.2)/132 (43)	1.21 (0.85-1.73)	0.304	1.29 (0.82-2.01)	0.287
Smoking status
Smokers	40 (13)/42 (13.7)	19 (6.2)/34 (11.1)	1.70 (0.84-3.46)	0.141	1.87 (0.89-3.94)	0.100
Non-smokers	126 (41)/99 (32.3)	118 (38.4)/136 (44.3)	1.47 (1.02-2.10)	0.037	1.51 (1.05-2.18)	0.028
Residence
Urban	89 (29)/79 (25.7)	84 (27.4)/84 (27.4)	1.13 (0.73-1.73)	0.585	1.17 (0.76-1.81)	0.479
Rural	77 (25.1)/62 (20.2)	53 (17.2)/86 (28)	2.02 (1.25-3.25)	0.004	2.35 (1.42-3.90)	0.001

¹Adjusted for age, sex, smoking status, residence, hypertension, and diabetes. OR: Odds ratio.