Ulcerative colitis in smokers, non-smokers and ex-smokers

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Jun 14, 2011 (publication date) through Nov 3, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Jun 14, 2011; 17(22): 2740-2747
Published online Jun 14, 2011. doi: 10.3748/wjg.v17.i22.2740

Table 2 Possible mechanisms in the pathogenic interactions of smoking and inflammatory bowel disease[64]

Modulation of cellular and humoral immunity

Changes in cytokine levels

Modification of eicosanoid-mediated inflammation

Reduction of antioxidant capacity, production of oxygen free radicals

Release of endogenous glucocorticoids

Colonic mucus effects

Alteration of mucosal blood flow

Pro-thrombotic effects and promotion of microvascular thrombosis

Alteration of gut permeability

Modification of gut motility

Citation: Bastida G, Beltrán B. Ulcerative colitis in smokers, non-smokers and ex-smokers. World J Gastroenterol 2011; 17(22): 2740-2747
URL: https://www.wjgnet.com/1007-9327/full/v17/i22/2740.htm
DOI: https://dx.doi.org/10.3748/wjg.v17.i22.2740