Enhanced proliferation, invasion, and epithelial-mesenchymal transition of nicotine-promoted gastric cancer by periostin

Figure 6 The inhibitory effect of periostin siRNA on nicotine-induced Snail protein expression. A: Western blotting bands of Snail protein in four groups of gastric cancer cells. B: Relative expression of Snail in the above four groups. Nicotine significantly increased the relative expression of Snail protein in gastric cancer cells (P < 0.05). However, there were no significant differences in Snail expression between the siRNA-P group and the siRNA-P+nicotine group (P > 0.05). Notes: siRNA-C: vacant siRNA-control; siRNA-P: Transfected with periostin; Ni: Treated by 200 ng/mL nicotine.