Keratinocyte growth factor gene therapy ameliorates ulcerative colitis in rats

Figure 7 Tumor necrosis factor-α concentration in homogenate of colon tissues. The concentration of tumor necrosis factor (TNF)-α in the homogenate was measured by enzyme-linked immunosorbent assay after administration. The expression of TNF-α decreased significantly in attenuated Salmonella typhimurium Ty21a strain carrying human keratinocyte growth factor gene (SPK) group from day 5 to day 10. Data are presented as mean ± SD, n = 6. ^aP < 0.05, ^bP < 0.01 vs attenuated Salmonella typhimurium Ty21a strain (SP) group; ^dP < 0.01 vs control group at the same time point.