Keratinocyte growth factor gene therapy ameliorates ulcerative colitis in rats

Figure 2 Histological sections of the colon on day 10 after treatment. Inflammatory cell infiltration and edema decreased evidently in attenuated Salmonella typhimurium Ty21a strain carrying human keratinocyte growth factor gene (SPK) group compared with attenuated Salmonella typhimurium Ty21a strain (SP) and control groups. Glands arranged more regularly and there was not obvious hyperemia in the lamina propria in SPK group. A: A representative colon from SPK group; B: A representative colon from SP group; C: A representative colon from control group. D: A representative colon from normal group (HE stain, × 200).