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©2011 Baishideng Publishing Group Co.
World J Gastroenterol. Jun 7, 2011; 17(21): 2602-2610
Published online Jun 7, 2011. doi: 10.3748/wjg.v17.i21.2602
Published online Jun 7, 2011. doi: 10.3748/wjg.v17.i21.2602
Table 2 Differentiation of low and high grade dysplasia and gastric carcinomas
| Histology | Feature | Low-grade dysplasia | High-grade dysplsia | Carcinoma |
| Structural atypia | Gland size | Uniform | Variable | Variable |
| Gland arrangement | Regular | Slightly irregular | Irregular | |
| Glandular crowding | Slight | Moderate | Marked | |
| Glandular transition to surrounding mucosa | No | No | No | |
| Glandular branching/budding | Focal | Prominent | Prominent | |
| Glandular cribriform | No | Yes | Yes | |
| Surface maturation | No | No | No | |
| Nuclear atypia | Shape | Elongated | Elongated and/or irregular | Oval/round |
| Pseudostratification | Basal 1/2 | Over basal 1/2 | Irregular | |
| Membrane | Thin | Thick | Uneven | |
| Hyperchromasia | Hyperchromatic even | Hyperchromatic irregular | Vesicular | |
| Pleomorphism | No | Mild | Moderate to marked | |
| Prominent nucleoli | Absent | Present | Present | |
| Loss of polarity | No | No/yes | Yes | |
| Stroma | Invasion | No | No | Yes |
- Citation: Kim JM, Cho MY, Sohn JH, Kang DY, Park CK, Kim WH, Jin SY, Kim KM, Chang HK, Yu E, Jung ES, Chang MS, Joo JE, Joo M, Kim YW, Park DY, Kang YK, Park SH, Han HS, Kim YB, Park HS, Chae YS, Kwon KW, Chang HJ, Pathologists TGPSGOKSO. Diagnosis of gastric epithelial neoplasia: Dilemma for Korean pathologists. World J Gastroenterol 2011; 17(21): 2602-2610
- URL: https://www.wjgnet.com/1007-9327/full/v17/i21/2602.htm
- DOI: https://dx.doi.org/10.3748/wjg.v17.i21.2602