siRNA targeting Livin decreases tumor in a xenograft model for colon cancer

Figure 3 Cell counting after small interfering RNA transfection in HCT116 cell line. We estimated cell count (%) of each groups in HCT116 cells after Livin silencing with 25, 50, 100, 150 and 200 μmol/L of siRNA. The cell count at 18 h after transfection was the most effectively reduced, but this effect was not time-dependent or dose-dependent. A: Cell count at 18 h post-transfection was significantly reduced as compared with control. (P < 0.01); B: Cell count at 24 h post-transfection; C: Cell count at 30 h post-transfection.