Connective tissue growth factor reacts as an IL-6/STAT3-regulated hepatic negative acute phase protein

doi:10.3748/wjg.v17.i2.151

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Jan 14, 2011 (publication date) through Oct 2, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Jan 14, 2011; 17(2): 151-163
Published online Jan 14, 2011. doi: 10.3748/wjg.v17.i2.151

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Figure 6 A simplified and schematic overview of the proposed interplay of interleukin-6 and tissue growth factor β1 on the regulation of CYR61/CTGF/NOV 2/connective tissue growth factor expression in hepatocytes and its relevance for inflammation, host defence and fibrogenesis in chronic liver disease. CTGF: Connective tissue growth factor; IL-6: Interleukin-6; TGF: Transforming growth factor.

Citation: Gressner OA, Peredniene I, Gressner AM. Connective tissue growth factor reacts as an IL-6/STAT3-regulated hepatic negative acute phase protein. World J Gastroenterol 2011; 17(2): 151-163
URL: https://www.wjgnet.com/1007-9327/full/v17/i2/151.htm
DOI: https://dx.doi.org/10.3748/wjg.v17.i2.151