CYP1A1 Ile462Val polymorphism contributes to colorectal cancer risk: A meta-analysis

Table 2 Odds ratio and 95% confidence interval of CYP1A1 Ile462Val polymorphism and colorectal cancer risk

Contrast	Racial descent	OR	95% CI	Ph
Val/Val vs Ile/Ile	Total	1.47	1.16-1.86	0.44
	European	1.43	0.83-2.48	0.93
	Asian	1.40	1.07-1.82	0.23
Ile/Val vs Ile/Ile	Total	1.28	0.96-1.72	< 0.011
	European	1.22	1.05-1.42	0.25
	Asian	0.91	0.79-1.05	0.19
(Val/Val + Ile/Val) vs Ile/Ile	Total	1.33	1.01-1.75	< 0.011
	European	1.24	1.07-1.43	0.24
	Asian	0.98	0.96-1.13	0.17
Val/Val vs (Ile/Val + Ile/Ile)	Total	1.49	1.18-1.88	0.77
	European	1.39	0.80-2.41	0.94
	Asian	1.46	1.12-1.89	0.24

¹Estimates for random effects.

P_h: Test for heterogeneity; CYP1A1: Cytochrome P450, including family 1, subfamily A, polypeptide 1; OR: Odds ratio; CI: Confidence interval.