Polymorphisms in NF-&kappa;B, PXR, LXR, PPAR&gamma; and risk of inflammatory bowel disease

doi:10.3748/wjg.v17.i2.197

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Jan 14, 2011; 17(2): 197-206
Published online Jan 14, 2011. doi: 10.3748/wjg.v17.i2.197

Table 2 Allele frequencies for the gene polymorphisms in Crohn’s disease and ulcerative colitis patients n (%)

	CD	UC	Controls
NF-κB -94ins/del
I	379 (58)	583 (59)	919 (59)
D	275 (42)	407 (41)	639 (41)
PPARγ Pro¹²Ala
C	564 (86)	844 (85)	1315 (84)
G	90 (14)	146 (15)	243 (16)
PPARγ C1431T
C	560 (86)	832 (84)	1327 (85)
T	94 (14)	158 (16)	231 (15)
PXR rs1523127
A	395 (60)	570 (58)	926 (59)
C	259 (40)	420 (42)	632 (41)
PXR rs2276707
C	540 (83)	825 (83)	1275 (82)
T	114 (17)	165 (17)	283 (18)
PXR rs6785049
A	426 (65)	615 (62)	1011 (65)
G	228 (35)	375 (38)	547 (35)
LXR rs1405655
T	435 (67)	675 (68)	1079 (69)
C	219 (33)	315 (32)	479 (31)
LXR rs2695121
T	292 (45)	430 (43)	727 (47)
C	362 (55)	560 (57)	831 (53)

NF-κB: Nuclear factor κB; PPARγ: Peroxisome proliferator-activated receptor γ; CD: Crohn’s disease; UC: Ulcerative colitis; PXR: Pregnane X receptor; LXR: Liver X receptor.

Citation: Andersen V, Christensen J, Ernst A, Jacobsen BA, Tjønneland A, Krarup HB, Vogel U. Polymorphisms in NF-κB, PXR, LXR, PPARγ and risk of inflammatory bowel disease. World J Gastroenterol 2011; 17(2): 197-206
URL: https://www.wjgnet.com/1007-9327/full/v17/i2/197.htm
DOI: https://dx.doi.org/10.3748/wjg.v17.i2.197