Pathologic pancreatic endocrine cell hyperplasia

Table 2 Summary of 8 cases of pancreatic polypeptide cell hyperplasia

Study	Tomita et al[60]	Farley et al[61]	Martella et al[62]	Pasieka et al[63]	Albazaz et al[64]	Bunning et al[65]
Location	USA	USA	Italy	Canada	UK	USA
Ethnicity	ND	ND	ND	ND	ND	ND
Age (yr)	70	66	50-70	37	76	71
Sex	F	M	3F	F	M	M
Clinical	Diarrhea	Diarrhea	ZES	Diarrhea	Bowel obstruction	Nausea ZES
PP (pg/mL) Pre-op	ND	Highly elevated	About 3 fold	ND	ND	ND
PP (pg/mL) Post-op	ND	ND	ND	ND	ND	ND
Imaging	Mass in pancreas head	Mass in pancreas head	Nonspecific	Normal	Mass in pancreas head	Normal
Octreotide scan	ND	ND	ND	ND	ND	Uptake in pancreas head
Pathology	PP cell hyperplasia	PP cell hyperplasia	PP cell hyperplasia	PP cell hyperplasia	PP cell hyperplasia	PP cell hyperplasia

ND: Not described; ZES: Zollinger-Ellison syndrome; PP: Pancreatic polypeptide.