Lapatinib-induced hepatitis: A case report

Table 1 Evolution of laboratory tests after lapatinib discontinuation

	SGPT (U/L)	SGOT (U/L)	ALP (U/L)	GGT (U/L)	TBIL (mg/dL)
Baseline (before initiation of capecitabine/lapatinib)	24	21	120	11	0.8
Ten days later (capecitabine discontinuation due to diarrhea)	30	22	110	20	0.7
Two weeks after capecitabine discontinuation (lapatinib discontinuation)	583	457	348	213	4.1
Two weeks after lapatinib discontinuation	481	589	310	294	11.8
1 mo after lapatinib discontinuation	260	238	318	160	2.7
2 mo after lapatinib discontinuation	229	180	298	140	2.3
3 mo after lapatinib discontinuation	44	36	246	42	0.9

SGPT: Serum glutamic pyruvic transaminase; SGOT: Serum glutamic oxaloacetic transaminase; ALP: Alcaline phosphatase; GGT: Gamma-glutamyl transpeptidase; TBIL: Total Bilirubin.