SPARCL1, Shp2, MSH2, E-cadherin, p53, ADCY-2 and MAPK are prognosis-related in colorectal cancer

doi:10.3748/wjg.v17.i15.2028

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Apr 21, 2011; 17(15): 2028-2036
Published online Apr 21, 2011. doi: 10.3748/wjg.v17.i15.2028

Table 3 Relationship between marker expression and clinical features (P values)

Markers	P values
Markers	Differentiation	pT	pN	pM	TNM	Post-surgery
P53	0.671	0.654	0.003^b	0.119	0.024^a	0.207
MAPK	0.186	0.597	0.230	0.188	0.182	0.001^b
E-cadherin	0.028^a	0.342	0.080	0.041^a	0.223	0.004^b
MSH2	0.964	0.006^b	0.012^a	0.061	0.001^b	0.001^b
ADCY-2	0.458	0.430	0.779	0.470	0.878	0.082
Shp2	0.020^a	0.004^b	0.035^a	0.849	0.006^b	0.006^b
SPARCL1	0.002^b	0.171	0.037^a	0.021^a	0.044^a	0.014^a

The relationship between the expression of candidate markers and some pathologic features was evaluated by Kruskal-Wallis test (SPSS Version 13.0 software) in immunohistochemistry analyses. All P values are two-sided (^aP < 0.05,

^bP < 0.01). The pathologic features in the table were differentiation, bowel wall invasion (pT), lymph node metastasis (pN), distant metastasis (pM), TNM stage (TNM), post-surgery recurrence or metastasis (Post-surgery).

Citation: Yu SJ, Yu JK, Ge WT, Hu HG, Yuan Y, Zheng S. SPARCL1, Shp2, MSH2, E-cadherin, p53, ADCY-2 and MAPK are prognosis-related in colorectal cancer. World J Gastroenterol 2011; 17(15): 2028-2036
URL: https://www.wjgnet.com/1007-9327/full/v17/i15/2028.htm
DOI: https://dx.doi.org/10.3748/wjg.v17.i15.2028