Down-regulation of miR-622 in gastric cancer promotes cellular invasion and tumor metastasis by targeting ING1 gene

Table 1 Clinicopathological features and miR-622 expression in gastric cancer patients

Factors	No. of patients	Mean expression of miR-622	P value
Age (yr)
< 65	42	4.84 ± 3.78	0.9731
≥ 65	15	4.89 ± 4.65
Gender
Male	30	5.51 ± 3.89	0.1911
Female	27	4.12 ± 4.03
Cell differentiation
Poor	19	5.71 ± 4.14	0.021a
Moderate	38	3.14 ± 3.07
Tumor size (cm)
< 5	48	4.60 ± 3.79	0.2591
≥ 5	9	6.24 ± 4.91
Gross appearance
Borrmann I + II type	10	3.72 ± 3.69	0.3251
Borrmann III + IV type	47	5.10 ± 4.04
Site of tumor
Cardia	9	3.60 ± 4.00	0.371
Body	8	3.84 ± 5.57
Antrum	40	5.34 ± 3.682
Lymphatic metastasis
Positive	31	6.03 ± 4.16	0.041a
Negative	26	3.87 ± 3.60
Depth of cancer invasion
T2	11	4.71 ± 5.03	0.5861
T3	44	5.02 ± 3.78
T4	2	2.02 ± 1.37
TNM Stage
I	2	0.82 ± 0.72	0.3851
II	12	4.02 ± 3.31
III	35	5.34 ± 4.12
IV	8	5.00 ± 4.49
Distal metastasis
Positive	6	3.67 ± 3.22	0.4441
Negative	51	5.00 ± 4.07

¹Chi-square test.

^aP < 0.05; TNM: Tumor-node-metastasis.